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	Provedor de dados AgEcon (1) Biol. Res. (1) BJMBR (1) Autor BEI,KRISTIJAN (1) BORASKA,VESNA (1) Bartholomeu,T. (1) Basso,L. (1) Cleves, Mario A. (1) Forjaz,C.L.M. (1) IKEŠ ULI,VEDRANA (1) KAPITANOVI,SANJA (1) Maia,J.A.R. (1) Oliveira,J.A. (1) Prista,A. (1) Rezende,J.A.S. (1) Tani,G. (1) ZEMUNIK,TATIJANA (1) ŠKRABI,VESELIN (1) Mais... Palavra-chave Genetic epidemiology (3) Biallelic marker (1) Croatia (1) Environmental influence (1) Exercise (1) Genetic linkage (1) Hardy–Weinberg (1) Heritability (1) Hwsnp (1) Hypertension (1) Polymorphism (1) QTL (1) Qtlsnp (1) Research Methods/ Statistical Methods (1) Single nucleotide polymorphisms (1) Tumor necrosis factor gene (TNF) (1) Type 1 diabetes (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Journal Article (1) Journal article (1) Ano 2012 (1) 2008 (1) 2005 (1) País Brazil (1) Chile (1) United States (1) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Association of TNF promoter polymorphisms with type 1 diabetes in the South Croatian population Biol. Res. BORASKA,VESNA; ŠKRABI,VESELIN; IKEŠ ULI,VEDRANA; BEI,KRISTIJAN; KAPITANOVI,SANJA; ZEMUNIK,TATIJANA. Type 1 diabetes mellitus (TIDM) is an autoimmune disease characterized by the destruction of pancreatic p cells. Tumor necrosis factor (TNF) is a pleotropic cytokine with potent immunomodulatory and inflammatory activity. Association studies of TNF polymorphisms and type 1 diabetes (TIDM) frequently demonstrated TNF involvement with TIDM. Although TNF may play an important role in the pathogenesis of TIDM, the genetic association of TNF región with the disease has not been conclusive because of the strong linkage disequilibrium with HLA genes. In this study, we examined two TNF promoter variants (rs 1800629 at position -308, and rs361525 at position -238) for TIDM association in 233 patients and 144 controls from the population of South Croatia. A higher... Tipo: Journal article Palavras-chave: Type 1 diabetes; Tumor necrosis factor gene (TNF); Polymorphism; Genetic epidemiology; Croatia. Ano: 2008 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000200005 Exploratory analysis of single nucleotide polymorphism (SNP) for quantitative traits AgEcon Cleves, Mario A.. With the decreasing cost and the increasing ability to quickly genotype single nucleotide polymorphisms (SNP) across the human genome, large databases containing possibly hundreds of typed SNPs are becoming common in population-based studies of quantitative traits. Testing for association between individual SNPs and the quantitative trait is an important first step in the discovery of disease susceptibility SNPs. This task, however, could be time-consuming and tedious if a large number of SNPs is involved. In this article, I introduce two new commands designed to facilitate the screening and testing of multiple SNPs for possible association with quantitative traits. Tipo: Journal Article Palavras-chave: Hwsnp; Qtlsnp; Genetic epidemiology; Genetic linkage; QTL; Biallelic marker; Single nucleotide polymorphisms; Hardy–Weinberg; Research Methods/ Statistical Methods. Ano: 2005 URL: http://purl.umn.edu/117508 Genetic and environmental influences on blood pressure and physical activity: a study of nuclear families from Muzambinho, Brazil BJMBR Forjaz,C.L.M.; Bartholomeu,T.; Rezende,J.A.S.; Oliveira,J.A.; Basso,L.; Tani,G.; Prista,A.; Maia,J.A.R.. Blood pressure (BP) and physical activity (PA) levels are inversely associated. Since genetic factors account for the observed variation in each of these traits, it is possible that part of their association may be related to common genetic and/or environmental influences. Thus, this study was designed to estimate the genetic and environmental correlations of BP and PA phenotypes in nuclear families from Muzambinho, Brazil. Families including 236 offspring (6 to 24 years) and their 82 fathers and 122 mothers (24 to 65 years) were evaluated. BP was measured, and total PA (TPA) was assessed by an interview (commuting, occupational, leisure time, and school time PA). Quantitative genetic modeling was used to estimate maximal heritability (h²), and genetic and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Exercise; Hypertension; Environmental influence; Heritability; Genetic epidemiology. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012001200023 Registros recuperados: 3 Primeira ... 1 ... Última

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